Zeiss Cell Explorer Services

Dr. Udo Kraushaar
Group Leader Electrophysiology

+49 7121 51530-851

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With attached Yokogawa spinning disk for rapid confocal imaging offers subcellular resolution with sampling frequencies up to 80 Hz.

Confocal Ca2+ imaging of cultivated, spontaneously beating cardiomyocytes using the Zeiss Cell Observer system. The top part of the picture below: Time series of false-color coded Ca2+ dependent fluorescence of Cal520-AM loaded cardiomyocytes. Excitation leads to a transient intracellular Ca2+ increase, visualized by a color shift from blue via green to red. Bottom: Fluorescence intensity-over time trace of above-shown recording. Numbers indicate the time points of the images.